The fifteenth episode of Season 16, and the three hundred and eighty-first episode of America's Got Talent overall, was aired on August 31, 2021. It was the first of two Semifinals performance episodes and took place at the Dolby Theatre. 11 acts performed for 5 spots in the Finals.
|1. Peter Rosalita||Singer|
|2. Michael Winslow||Voicetramentalist|
|3. Beyond Belief Dance Company||Dance Group|
|4. Aidan Bryant||Aerialist|
|5. Tory Vagasy||Singer|
|6. World Taekwondo Demonstration Team||Martial Arts Group|
|7. Madilyn Bailey||Singer|
|8. Dustin Tavella||Magician|
|9. Korean Soul||Band|
|10. Gina Brillon||Stand-Up Comedienne|
|11. Jimmie Herrod||Singer|
- This was the first live show of Season 16 where no acts got buzzed. It was followed by Episode 1619.